if you are using a static page as homepage, and try to show many post in this page,you use code like
 10,
        'paged' => $paged,
    );
    query_posts($args);?>          
to get pagination work,but it do not work,i searched a lot ,eventrually find the answer. just use
get_query_var('page')          
instead,i do not know why,but it will work.